PROLONGATION OF THE Q-T INTERVAL (ROMANO-WARD SYNDROME): ANAESTHETIC MANAGEMENT

Prolongation of the Q-T interval (Romano-Ward syndrome): anaesthetic management.

The anaesthetic management is described of a patient with prolonged Q-T interval which had been complicated by ventricular fibrillation at induction of general anaesthesia for a previous operation. This complication was prevented by effective premedication with i.v. propranolol and block of the left stellate ganglion.

Q-T interval prolongation in cirrhosis: Relationship and severity

Background: Cirrhosis as the final stage of progressive fibrosis of liver can affect other organs such as lungs, kidneys and heart. "Cirrhotic cardiomyopathy" involves the electrophysiological abnormalities such as QT interval prolongation. We assessed correlation between corrected QT interval prolongation and severity of cirrhosis based on Child Classification in each ECG lead. ...

A recessive variant of the Romano-Ward long-QT syndrome?

BACKGROUND The congenital long-QT syndrome (LQTS) is a genetically heterogeneous disease characterized by prolonged ventricular repolarization and life-threatening arrhythmias. Mutations of the KVLQT1 gene, a cardiac potassium channel, generate two allelic diseases: the Romano-Ward syndrome, inherited as a dominant trait, and the Jervell and Lange-Nielsen syndrome, inherited as an autosomal rec...

Epilepsy: a presentation of the Romano-Ward syndrome.

Romano-Ward Long QT Syndrome Analysis of 23 Families

Background The Romano-Ward long-QT Syndrome (LQTS) is an autosomal dominant inherited trait characterized by prolonged QT interval on ECG, life-threatening arrhythmias, syncope, and sudden death in affected individuals. A gene responsible for this disorder has been shown to be linked to the Harvey ras-1 locus (H-ras-1) DNA marker on the short arm of chromosome 11 (llp) in 7 families. The purpos...